Vision and cognition in Alzheimer's disease.

نویسندگان

  • M Rizzo
  • S W Anderson
  • J Dawson
  • M Nawrot
چکیده

Alzheimer's disease (AD) is known to affect visual pathways, but potential concomitant effects on vision and cognitive performance are not well understood. We studied 43 individuals with AD of mild severity and 22 individuals without dementia on a battery of tests designed to measure multiple aspects of basic and higher-order visual perception and cognition. All subjects performed on the same visual and cognitive test batteries. The results showed no differences between groups on tests of static visual acuity, stereoacuity, dynamic visual acuity or motion direction discrimination. However, individuals with AD performed significantly worse on tests of static spatial contrast sensitivity, visual attention, shape-from-motion, color, visuospatial construction and visual memory. Correlation analyses showed strong relationships between visual and cognitive scores. The findings show that AD affects several aspects of vision and are compatible with the hypothesis that visual dysfunction in AD may contribute to performance decrements in other cognitive domains. The pattern of involvement indicates that AD affects multiple visual neural pathways and regions. It is possible that better understanding of vision-related dysfunction could aid diagnosis and interventions to improve functional capacity in patients with dementia.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The effect of cognitive therapy on cognition in elderly people with Alzheimer's disease: A review article

Introduction and purpose: Elderly people often face cognitive problems due to the aging process. Decreased ability in cognitive functions leads to impaired performance in daily activities of judgment, attention, and awareness. Therefore, this study investigates different cognitive therapies on cognition in elderly people with Alzheimer's disease. Materials and Methods: Prisma method was used i...

متن کامل

Evaluation of Visual Signs and Symptoms in Patients with Alzheimer's Disease

Background and Objective:Patients with Alzheimer's disease have impaired visual function even in the early stages of the disease. Therefore, the present study aimed to determine the visual signs and symptoms in patients with Alzheimer's disease and compare them with those in the control group. Materials and Methods:This cross-sectional descriptive study was conducted on 19 Alzheimer patients a...

متن کامل

Effects of Active Constituents of Crocus sativus L., Crocin on Streptozocin-Induced Model of Sporadic Alzheimer\'s Disease in Male Rats

Background: The involvement of water-soluble carotenoids, crocins, as the main and active components of Crocus sativus L. extract in learning and memory processes has been proposed. In the present study, the effect of crocins on sporadic Alzheimer's disease induced by intracerebroventricular (icv) streptozocin (STZ) in male rats was investigated. Methods: Male adult Wistar rats (n = 90 and 260-...

متن کامل

Vision in Alzheimer's disease.

In order to assess vision in Alzheimer's disease (AD) and related disorders, gerontologists must use tests that make minimal cognitive demands on the subject. Using such tests, we have found a pattern of deficits in color discrimination, stereoacuity, contrast sensitivity, and backward masking that differs from that seen in healthy elderly individuals. Impaired vision predicts deficient perform...

متن کامل

Colour vision deficiencies in Alzheimer's disease.

OBJECTIVE visual disorders are among the earliest symptoms of Alzheimer's disease. It is, however, still controversial as to whether Alzheimer's disease impairs colour vision. In this study, colour vision of Alzheimer's disease patients was tested using the Ishihara test and the PV-16 choice test. The latter test, primarily designed for children, was chosen in order to avoid problems due to cog...

متن کامل

ارزیابی عملکرد بینایی ـ فضایی در بیماران آلزایمری و افراد مسن سالم با استفاده از روش تکلیف دوگانه

Background and Objective: The purpose of this study was the evaluation of visuospatial task performance in elderly patients with and without Alzheimer's disease using the dual task. Materials and Methods: This study was a quasi-experimental and between subjects and within subjects design was used in it. The 23 subjects (11 females and 12 males) with an age range of 62 to 81 years 13 patients w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Neuropsychologia

دوره 38 8  شماره 

صفحات  -

تاریخ انتشار 2000